Amazing Cajun Beef Spaghetti with Three-Cheese Sauce

If you love bold flavors and creamy pasta dishes, this Amazing Cajun Beef Spaghetti with Three-Cheese Sauce will quickly become a favorite. This delicious recipe pairs spicy Cajun-seasoned beef with a rich blend of Parmesan, mozzarella, and cheddar cheese sauce, all served over perfectly cooked spaghetti. It’s a wonderful combination that delivers comfort and excitement in every bite.

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Why You’ll Enjoy This Cajun Beef Spaghetti

Cajun Beef Spaghetti is perfect for busy nights when you want a hearty yet easy meal. Ready in just 30 minutes, this recipe brings together creamy textures and savory seasonings quickly and effortlessly. The Cajun spices give the spaghetti a vibrant kick that balances the indulgence of the melted cheese sauce, making it an ideal dish for family dinners or casual gatherings.

Cajun Beef Spaghetti
Lucy C. Frakes

Amazing Cajun Beef Spaghetti with Three-Cheese Sauce

This creamy and spicy Cajun Beef Spaghetti combines Cajun-seasoned ground beef with a rich three-cheese sauce made from Parmesan, mozzarella, and cheddar, served over perfectly cooked spaghetti. Ready in just 30 minutes, it’s a comforting yet vibrant pasta dinner that brings bold Louisiana-inspired flavor to your table.
Prep Time 10 minutes
Cook Time 20 minutes
Total Time 30 minutes
Servings: 4 plates
Course: Main Course
Cuisine: American, Cajun
Calories: 570

Ingredients
  

  • 8 oz spaghetti
  • 1 lb ground beef
  • 1 tbsp Cajun seasoning
  • 1 tsp garlic powder
  • 1 tsp onion powder
  • 1/2 tsp black pepper
  • 1/4 tsp salt
  • 1 tbsp olive oil
  • 1 cup heavy cream
  • 1/2 cup grated Parmesan cheese
  • 1/2 cup shredded mozzarella cheese
  • 1/2 cup shredded cheddar cheese
  • 1/4 cup chopped green onions (for garnish)

Equipment

  • large pot
  • skillet
  • mixing spoon
  • colander
  • cheese grater

Method
 

  1. Boil salted water and cook spaghetti according to package instructions until al dente. Drain well and toss with a little olive oil to prevent sticking.
  2. In a hot skillet, brown the ground beef in olive oil for about 5–7 minutes, breaking it apart as it cooks. Drain any excess fat.
  3. Add Cajun seasoning, garlic powder, onion powder, salt, and pepper to the browned beef. Stir and cook for 2 minutes to blend flavors.
  4. Reduce heat and pour in heavy cream. Add Parmesan, mozzarella, and cheddar cheeses, stirring continuously until melted and creamy.
  5. Add cooked spaghetti to the cheese sauce and toss to coat. Heat for 2–3 minutes until warmed through.
  6. Serve hot, garnished with chopped green onions for a fresh flavor finish.

Nutrition

Calories: 570kcalCarbohydrates: 30gProtein: 35gFat: 35gSaturated Fat: 18gPolyunsaturated Fat: 2gMonounsaturated Fat: 10gTrans Fat: 1gCholesterol: 110mgSodium: 600mgPotassium: 480mgFiber: 2gSugar: 3gVitamin A: 450IUVitamin C: 3mgCalcium: 290mgIron: 3.2mg

Notes

Adjust the Cajun seasoning for your spice preference. For a lighter version, substitute Greek yogurt and milk for heavy cream. You can swap beef for mushrooms or lentils to make it vegetarian, or use gluten-free pasta for dietary needs. Leftovers store up to 3 days refrigerated; reheat with a splash of milk or cream to restore creaminess.

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Ingredients for Cajun Beef Spaghetti

Main Components

  • 8 ounces spaghetti
  • 1 pound ground beef (try ground turkey or chicken for a healthier twist)

Seasonings and Spices

  • 1 tablespoon Cajun seasoning
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • 1/2 teaspoon black pepper
  • 1/4 teaspoon salt

Sauce Ingredients

  • 1 tablespoon olive oil
  • 1 cup heavy cream (or substitute Greek yogurt mixed with low-fat milk)
  • 1/2 cup grated Parmesan cheese
  • 1/2 cup shredded mozzarella cheese
  • 1/2 cup shredded cheddar cheese

Garnish

  • 1/4 cup chopped green onions for a fresh finish
Cajun Beef Spaghetti with Three-Cheese

Step-by-Step Guide

Step 1 – Cook the Spaghetti

Boil salted water and cook spaghetti according to package instructions until al dente. Drain well, then toss with a little olive oil to prevent sticking.

Step 2 – Brown the Beef

In a hot skillet, brown the ground beef in olive oil, breaking it apart as it cooks for about 5-7 minutes. Remove excess fat for a leaner dish.

Step 3 – Season the Beef

Add Cajun seasoning, garlic powder, onion powder, salt, and pepper to the browned beef. Stir well and cook for 2 minutes to blend the flavors.

Step 4 – Make the Cheese Sauce

Reduce the heat and pour in heavy cream. Add Parmesan, mozzarella, and cheddar cheeses. Stir continuously until the cheese melts into a creamy sauce.

Step 5 – Combine and Finish

Add the cooked spaghetti to the cheese sauce, tossing gently to coat every strand. Heat for 2-3 minutes to warm through.

Step 6 – Garnish and Serve

Serve hot, garnished with chopped green onions for a burst of fresh flavor and color.

Cajun Beef Spaghetti with Three-Cheese Sauce recipe

Pro Tips for Perfect Cajun Beef Spaghetti

  • Salt the pasta water generously to enhance flavor.
  • Use low heat to melt cheese smoothly without scorching.
  • Brown beef thoroughly to deepen the dish’s flavor.
  • Adjust Cajun seasoning to your preferred spice level.
  • Fresh cheeses improve taste and texture noticeably.

Flavor Variations for Cajun Beef Spaghetti

  • Swap beef for mushrooms or lentils for a vegetarian version.
  • Add greens like spinach or kale just before serving.
  • Choose gluten-free pasta for dietary restrictions.
  • Include jalapeños or hot sauce for extra spice.

Serving Suggestions

Pair this Cajun beef spaghetti with crunchy garlic bread or a crisp green salad dressed in light vinaigrette to balance the richness.

Cajun Beef Spaghetti with Three-Cheese Sauce

Storage Tips

Store leftovers in an airtight container in the fridge for up to three days. Reheat gently, adding a splash of milk or cream to restore creaminess. Avoid freezing to maintain the sauce’s texture.

Nutrition Information Per Serving

CaloriesProteinCarbsFatFiberSodium
57035g30g35g2g600mg

Frequently Asked Questions About Cajun Beef Spaghetti

Can I prepare Cajun beef spaghetti in advance?

Yes, cook the pasta and sauce separately ahead of time. Store refrigerated and combine before serving, reheating gently.

What’s a good substitute for heavy cream in this dish?

Half-and-half or a yogurt and milk blend works well for a lighter sauce.

How spicy is this Cajun beef spaghetti?

The spice depends on the Cajun seasoning used. Adjust quantity or add jalapeños for desired heat.

Can I use different types of pasta?

Yes, penne, fettuccine, or gluten-free noodles all make great alternatives.

How do I store leftovers?

Keep refrigerated up to three days in an airtight container, reheating gently with cream or milk.

Final Thoughts

This Cajun Beef Spaghetti with Three-Cheese Sauce offers a flavorful and creamy pasta dinner that’s quick and satisfying. Its balance of spices, creamy cheese, and hearty beef makes it a great choice for any night of the week.

Ready to enjoy a fresh and satisfying meal? Try making this Chicken Caesar Pasta Salad today! Packed with tender chicken, crisp greens, and creamy dressing, it’s the perfect dish for easy lunches or light dinners.

For detailed nutrition data on ingredients like beef, cheese, and pasta, explore the official USDA FoodData Central database, a trusted government source for accurate food information. Click here to start your delicious and nutritious Chicken Caesar Pasta Salad journey now!